Neither side are in with a shot of advancing to the last 32, with Tottenham Hotspur and Royal Antwerp left to battle it out for the top two spots in Group J.
LASK's slim hopes of progressing from the group were ended in last week's thrilling 3-3 draw with Tottenham, which they needed to win.
Incredibly, there was still time for Mamoudou Karamoko to score a leveller, taking the Austrian side to seven points from their five matches.
That is seven points more than opponents Ludogorets have managed, having lost all five matches so far by an aggregate score of 16-6.
They are one of only three pointless sides heading into the final round of fixtures, along with Dundalk and Gent.
The Bulgarian outfit most recently went down 3-1 to Royal Antwerp, while at home they have lost their last four matches in Europe - their worst ever such run.
In fact, Ludogorets could become the first ever Bulgarian team to lose all six Europa League group stage games in a season, following Levski Sofia's run of five in 2009-10 and 2010-11.
It may only be pride on the line for LASK, though a victory for them would make it consecutive away victories in a major UEFA European competition for the first time in their history.
Ludogorets Razgrad Europa League form: LLLLL
Ludogorets Razgrad form (all competitions): LWLWLW
LASK Linz Europa League form: LWWLD
LASK Linz form (all competitions): WDLWDW
It remains to be seen what level of side both managers field given there is no chance of advancing any further.
Romania international Claudiu Keseru is the biggest threat in Ludogorets's side, though he has scored only once in four group matches so far.
Including own goals, LASK's eight goals in this season's Europa League have been scored by seven different players, with only Eggestein (two) scoring more than once.
Lukas Grgic was back involved in the Austrian side's win over Admira and will start this match if deemed ready.
Ludogorets Razgrad possible starting lineup:
Stoyanov; Ikoko, Verdon, Grigore, Nedyalkov; Andrianantenaina, Badji; Despodov, Cauly, Tchibota; Keseru
LASK Linz possible starting lineup:
Schlager; Wiesinger, Trauner, Andrade; Ranftl, Michorl, Holland, Renner; Gruber, Balic, Eggestein
We say: Ludogorets Razgrad 2-1 LASK Linz
Ludogorets, who beat Slavia Sofia 2-0 in their domestic league at the weekend, have followed up each of their last four victories with a defeat.
Beyond that, the hosts have showed little in this campaign to suggest they can pick up a first point against a LASK side that will no doubt be disappointed to be heading out.