Renewing an increasingly fierce European rivalry, a revitalised Liverpool host 15-time continental champions Real Madrid at Anfield in Tuesday's Champions League headline act.
Arne Slot's crop finally stopped the domestic rut on Saturday night, strolling to a 2-0 Premier League win over Aston Villa thanks to Mohamed Salah and Ryan Gravenberch's goals.
The Reds were also relentless in their last European affair, pummelling Eintracht Frankfurt 5-1 in Germany to move up to 10th in the 36-team league phase table.
Here, Sports Mole rounds up Liverpool's latest injury and suspension news ahead of their clash with Real Madrid, who have a perfect nine points on the board in the 2025-26 Champions League so far.
Giovanni Leoni
Status: Out
Type of injury: ACL
Possible return date: Unknown
Giovanni Leoni's debut season at Anfield has been cruelly cut short by a devastating ACL injury, one that is likely to rule him out until the summer months.
Alisson Becker
Status: Out
Type of injury: Hamstring
Possible return date: November 22 (vs. Nottingham Forest)
Alisson Becker came off with a hamstring problem in Liverpool's Champions League defeat to Galatasaray in September, and the Brazilian will not be back before the international break.
Jeremie Frimpong
Status: Out
Type of injury: Hamstring
Possible return date: November 22 (vs. Nottingham Forest)
Jeremie Frimpong was a casualty of Liverpool's last UCL game against Frankfurt with a hamstring concern, and the Dutchman is not expected back in action until the end of November or start of December.
Alexander Isak
Status: Out
Type of injury: Groin
Possible return date: November 9 (vs. Man City)
Alexander Isak also succumbed to injury at the Deutsche Bank Park - damaging his groin - and after missing out against Villa at the weekend, the Sweden international will not be back on Tuesday.
Curtis Jones
Status: Minor doubt
Type of injury: Groin
Possible return date: November 4 (vs. Real Madrid)
Curtis Jones is also nursing a groin injury that he sustained against Brentford two Saturdays ago, but he has trained with the squad ahead of this fixture and seemingly has a strong chance of being involved.
LIVERPOOL SUSPENSION LIST
Liverpool have no players suspended for this game, but Conor Bradley is one yellow card away from incurring a Champions League ban.