Maddison and Pereira, who have recovered from respective hip and hamstring injuries, came off the bench in the defeat to Manchester City last weekend and are now in contention to start at the expense of Ayoze Perez and Marc Albrighton.
Perez, who has started the last three games in all competitions, is set to drop out despite recording three goals and three assists in his last seven Premier League starts against West Ham.
Brendan Rodgers confirmed that defender Caglar Soyuncu was missing last weekend after testing positive for coronavirus while on international duty with Turkey and as a result, the 24-year-old is highly unlikely to feature on Sunday.
Striker Kelechi Iheanacho is fit and firing and will be hoping to build on a return of seven goals in his last five appearances for the Foxes.
Leicester City possible starting XI: Schmeichel; Amartey, Evans, Fofana; Pereira, Tielemans, Ndidi, Castagne; Maddison; Vardy, Iheanacho
Watch the Sports Mole Football Shorts prediction for this game below: