The Italian champions will take on Celtic in the last 16, the first leg of which will be played in Glasgow on Tuesday.
"Juventus are back at top level of European football again - and we believe this could be our year," he told the Scottish Sun.
"We showed in the two games against the current European Champions Chelsea that we should now be taken very seriously.
"We have got a squad full of quality - and there is a real determination that this will not just be our season in Italy but also in Europe."
Buffon added that Juventus are not underestimating Celtic and admits that winning in Glasgow will be difficult.
"We are taking Celtic very seriously for sure," said the 35-year-old.
"Not just in beating Barcelona, but their performance in the group stages in general showed they are a very dangerous team.
"Especially in Glasgow it will be very tough. All the Celtic supporters will be fired up - but we are normally used to playing in such atmospheres."
Juventus last won the Champions League in 1996.