Espanyol are rock bottom of the table and had their relegation confirmed earlier this month, but Celta are currently 17th, only a point above 18th-placed Leganes.
Next season will be the first time that Espanyol have played outside of Spain's top tier since the 1993-94 campaign, with the Catalan outfit's relegation confirmed away to Barcelona on July 8.
The White and Blues have only won five of their 37 league matches this season, suffering 23 defeats in the process, to prop up the division with 24 points, 12 points behind Celta.
There is no question that Espanyol have seriously underachieved this term considering the talent in their squad, while they will enter this match off the back of eight straight league defeats.
Not since a goalless draw with Getafe on June 16 have the Catalan side avoided defeat in La Liga, and they suffered a 1-0 loss away to Valencia in their last game on Thursday night.
Espanyol only have pride to play for this weekend, but the same cannot be said for Celta, who are not yet sure of a spot in Spain's top flight for the 2020-21 campaign.
Mallorca have also been relegated, but 18th-placed Leganes are only a point off Celta in the table, meaning that either club could be relegated alongside Espanyol and Mallorca on Sunday.
The fact that Leganes are at home to Real Madrid could leave Celta with some breathing room, although the Sky Blues will not be taking any chances and will be determined to secure all three points in this game.
Oscar Garcia's side are actually without a win in Spain's top flight since June 24, losing three and drawing three of their last six, including defeats to Osasuna and Levante in their last two matches.
Interestingly, each of the last four league meetings between Espanyol and Celta have finished level, while Os Celestes have not actually beaten the Catalan club in La Liga since September 2016.
Espanyol La Liga form: LLLLLL
Celta La Liga form: DLDDLL
Espanyol will be without the services of three key players this weekend through suspension as Sergi Darder, Raul de Tomas and Bernardo Espinosa all picked up yellow cards against Valencia last time out.
Sebastien Corchia is still on the sidelines through injury, but the home side do not have any fresh fitness concerns, meaning that there are not expected to be any major surprises in the first XI.
Iago Aspas will again lead the line if Chalov is unable to recover from injury, although the former could be moved into a wider position if the latter can prove his fitness.
Espanyol possible starting lineup:
Diego Lopez; Avila, Cabrera, Naldo, Vila; Embarba, David Lopez, Roca, Melendo; Calleri, Wu Lei
Celta possible starting lineup:
Villar; Vazquez, Murillo, Araujo, Olaza; Beltran, Yokuslu, Bradaric; Mina, Aspas, Mendez
We say: Espanyol 1-2 Celta Vigo
Celta have only picked up two away wins in the league this season, but Espanyol have the worst home record in the division with just two victories. We are expecting a tight game at the RCDE Stadium but fancy Celta to pick up the result that they need to guarantee survival at this level of football.