The Argentine striker will be supported in attack by Fredy Guarin and Wesley Sneijder, with Esteban Cambiasso anchoring the midfield for the Nerazzurri.
Samir Handanovic will be between the posts for Inter in this Serie A fixture.
Hosts Chievo will have David di Michele and Sergio Pellissier as their two centre-forwards.
Chievo: Sorrentino, Dainelli, Cesar, Sardo, Frey, M. Rigoni, L. Rigoni, Vacek, Hetemaj, Di Michele, Pellissier
Inter Milan: Handanovic, Zanetti, Ranocchia, Samuel, Juan, Nagatomo, Pereira, Sneijder, Guarin, Cambiasso, Milito