Both men are suspended after picking up cards during last week's 1-1 draw at Real Sociedad, with Laporte's late dismissal failing to cost his team a point at the Anoeta Stadium.
After a disappointing start to the campaign, Bilbao have won three out of their last six fixtures in all competitions and currently sit in 10th position in the La Liga standings.
Last year's league champions are currently on a run of three games without a win in all competitions but with Real Madrid competing at the Club World Cup, they could cut the gap at the top to four points.
Form in La Liga: WDWWLD
Form in all competitions: WDLWDW
Possible starting lineup: Iraizoz, San Jose, Balenziaga, Bustinza, Susaeta, Benat, Mikel Rico, Aduriz, Muniain, De Marcos, Unai Lopez
Form in La Liga: WLWWWL
Form in all competitions: WWWDLD
Possible starting lineup: Moya; Juanfran, Miranda, Godin, Siqueira; Tiago, Gabi; Griezmann, Turan, Garcia; Cerci
Sports Mole says: 1-2