Ahead of Brook's fight against Shawn Porter for the IBF welterweight title, Khan has warned his fellow Brit that he would not consider agreeing to a bout unless he becomes a world champion.
"Kell Brook is not one I will be looking at," the 27-year-old is quoted as saying by The Mirror. "He doesn't deserve it - unless he fights Porter and beats Porter.
"If he had the IBF title, then maybe. He doesn't bring anything to the table without that. I just think it is wrong that he has made such a big name for himself in the UK fighting nobodies and trying to set up a big fight with me because he knows it will make him the biggest money of his career.
"He knows if he fights me, he makes a lot of money, and he doesn't deserve the money."
Brook has won all 32 of his professional fights.