Murray, who is promoted by Hatton, takes on WBC middleweight champion Martinez in Argentina.
The Lancashire fighter earned a credible draw in his last world title fight against Felix Sturm, and Hatton thinks that putting more pressure on his opponent towards the end will see Murray get the win.
"Martin's preparations in this camp have been faultless," said Hatton.
"I think in the Felix Sturm fight, he learned so much from when he went into the lion's den. But against Sturm, when the fight was in the balance, I don't think Martin grabbed the bull by the horns so to speak.
"But this time he knows that down the home straight he's going to have to jump all over Sergio and rip that title from him. I've seen a change in Martin this week, he's got a bit of a nasty head on him, a nasty streak which pleases me."
Murray is unbeaten in his 26 fights with one draw, while Martinez has won 50 of his 54 fights.