The reigning MVP scored nine of his 16 attempts from three-point range on the way to recording 40 points, eight assists and six rebounds in a 135-116 triumph over the Phoenix Suns.
It was another disappointing night at the opposite end of the NBA as the Philadelphia 76ers set a new record for the longest losing streak in US sports history by suffering a 116-114 defeat to the Houston Rockets.
The Sixers have lost 27 games in a row dating back to last season and are now 0-17 for the current campaign after James Harden scored 50 points to hold off a fourth-quarter comeback from Philadelphia.
Andrew Wiggins scored 22 points, while Zach LaVine added 19 points on his return to the starting lineup to help the Wolves to their eighth win.
Results in full: Cleveland Cavaliers 95-90 Charlotte Hornets, Milwaukee Bucks 90-114 Orlando Magic, Washington Wizards 78-111 Boston Celtics, Miami Heat 97-78 New York Knicks, Chicago Bulls 92-104 Indiana Pacers, Philadelphia 76ers 114-116 Houston Rockets, Atlanta Hawks 116-101 Memphis Grizzlies, Detroit Pistons 87-103 Oklahoma City Thunder, San Antonio Spurs 91-80 Denver Nuggets, Golden State Warriors 135-116 Phoenix Suns, Minnesota Timberwolves 101-91 Sacramento Kings, New Orleans Pelicans 90-111 Los Angeles Clippers