Spiller established himself as one of the most dangerous running backs in the league last year, rushing for 1,244 yards overall and reaching the 1,000 mark in fewer carries than anyone had managed since 1934.
Hackett is keen to take full advantage of Spiller's running ability, and he believes that his new tactic will pile the pressure on the opposition's defensive coordinator.
"It's real simple, we're going to give [Spiller] the ball until he throws up. So he's either got to tap out or throw up on the field. Let's just put it that way," Hackett told WGR 550.
"The great thing now is that we have some awesome weapons on the outside [at wide receiver], if you do want to stop [Spiller].
"Switching to this system and the tempo we've created, it's a completely different way that we call the game. It's more of an attacking thing, and you get to put pressure on the defensive coordinator."
Spiller, who was the ninth overall pick in the 2010 Draft, led the NFL in yards per carry last season.