The Tottenham Hotspur keeper made a costly error in Les Bleus' World Cup qualifying defeat to Sweden on Friday night, straying well off his line and being caught out by Ola Toivonen after playing a poor clearance into the opposition player's path.
On the eve of the friendly clash with England at the Stade de France, Deschamps stressed that Lloris remains important to his side, while teammate Raphael Varane also backed the 30-year-old to recover.
"He will play, definitely. Lloris will captain," Deschamps told reporters. "I discussed it with him and included that in my thinking. We shared the same opinion, that's clear. We want him to go back on the pitch."
Varane added: "I personally told him what I thought about him and that that this didn't change anything. We all make mistakes. He will continue saving us in other games and we don't have to cry over spilt milk."