Fijian Sireli Naqelevuki, who scored a dramatic winning try last time these two teams met, returns in place of the injured Jason Shoemark while Chris Whitehead, Tom Hayes and Aly Muldowney give the forwards a fresh feel for the Chiefs.
The returning Dean Schofield will captain the side while Chris Jones comes in at number eight. The Warriors have also made one change in the back line, bringing in Josh Drauniniu to play against his former club.
Exeter: Arscott, Camacho, Naqelevuki, Dollman, Jess, Steenson, Thomas; Sturgess, Whitehead, Rimmer, Hayes, Muldowney, Mumm, Scaysbrook, Baxter
Replacements: Clark, Moon, Budgen, Hanks, Ewers, Barrett, Mieres, Whitten
Worcester: Pennell, Drauniniu, Grove, Matavesi, Lemi, Goode, Hodgson; Jones, Shervington, Andress, Percival, Schofield, Betty, Kvesic, Jones
Replacements: Lutui, Mullan, Currie, Gillies, Taulava, Arr, Carlisle, Fatiaki