Young winger Marland Yarde has been passed fit and will make the London Irish 15 for the trip to Salford to take on the Sale Sharks on Friday night.
For the home side, David Seymour will captain a side that includes Danny Cipriani at number 10 and Mark Cueto at 14.
For the visitors, as well as the return of Yarde, Sailosi Tagicakibau replaces Jonathan Joseph and Darren Allinson makes his first start of the season at scrum half.
George Skivington is fit for Irish, however he only makes the replacements.
Sale: Macleod, Cueto, Leota, Tuitupou, Shepherd, Cipriani, Willis, Harrison, Taylor, Buckley, Gray, McKenzie, Vernon, Seymour, Powell
Replacements: Ward, Lewis-Roberts, Cobilas, Myall, Easter, Peel, Miller, Brady
London Irish: Watson, Ojo, Armitage, Tagicakibau, Yarde, Humphreys, Allinson, Lahiff, Lawson, Aulika, Evans, Garvey, Danaher, Gibson, Hala'ufia
Replacements: Blaney, Griffiths, Halavatau, Skivington, Treviranus, Shingler, Geraghty, Moates
