The league's bottom-placed side are currently five points from safety following one win in their last five games.
Seventh-placed Exeter are on a similarly poor run of form with no wins in their previous three matches.
Sale: Miller, Amesbury, Leota, Tuitupou, Cueto, Cipriani, Peel, Harrison, Taylor, Thomas, Holmes, Myall, Braid, Seymour Captain, Gaskell
Replacements: Jones, Dickinson, Buckley, McKenzie, Vernon, Cliff, Macleod, Addison
Exeter: Arscott, Votu, Naqelevuki, Shoemark, Nowell, Steenson, Chudley, Moon, Clark, Tui, Hayes, Mumm, White, Scaysbrook, Baxter
Replacements: Yeandle, Rimmer, Brown, Muldowney, Horstmann, Thomas, Mieres, Dollman
Sports Mole says: Exeter to increase Sale's problems