The first try of the encounter came through Christian Wade in the 18th minute.
Wade began the move before laying off to Charles Piutau, who found Elliot Daly, the centre cutting through the Gloucester defensive line before finding Wade who finished the move he started.
Fly-half Ruaridh Jackson added the extra two points from the boot to give Wasps a 10-0 lead.
A Gloucester scrum resulted in a Wasps penalty, which Daly again converted from long distance, before adding his third from the boot with a 47-metre effort as Wasps went into half time with a 16-0 lead.
The second period began with a red card for Gloucester as David Halaifonua was given his marching orders after a high tackle on Davies.
Gloucester finally got on the board in the 48th minute as Scotland scrum-half Greg Laidlaw split the posts with a penalty.
Wasps responded with a driving maul from their pack which resulted in a penalty try being awarded.
Jackson converted once more to make it a 20-point lead for Wasps with 52 minutes played.