Spurs have begun the new Premier League season in positive fashion, taking seven points from a possible 12 so far. Their last outing came on Saturday with a 2-2 draw at Sunderland.
Meanwhile, Partizan are currently at the top of their domestic league with a perfect record of five wins out of five.
The Serbians, who are managed by Marko Nikolic, dropped down to the Europa League after suffering a shock defeat to Ludogorets Razgrad in Champions League qualifying.
Possible starting lineups
Partizan: Lukac; Ilic, Vulicevic, Stankovic, Petrovic; Drincic, Grbic, Markovic, Pantic; Lazovic, Skuletic
Spurs: Lloris; Dier, Kaboul, Chiriches, Rose; Capoue, Dembele; Eriksen, Stambouli, Chadli; Adebayor
Sports Mole says: 1-2