The Italian coach is without both Xabi Alonso and Raphael Varane for their trip to the Estadio Nuevo Los Carmenes, but Isco is expected to retain his place in the starting lineup after scoring the decisive goal against Betis on his debut.
If Gareth Bale signs for Madrid before Monday, he is unlikely to feature due to injury.
Real Madrid: W
Granada: Roberto; Diakhate, Angulo, Nyom, Murillo; Yebda, Iturra, Brahimi, Dani Benitez, Piti; El-Arabi
Real Madrid: Diego Lopez, Sergio Ramos, Pepe, Marcelo, Daniel Carvajal; Modric, Ozil, Khedira, Isco; Cristiano Ronaldo, Benzema
Sports Mole says: 1-4