The Red Devils are currently fourth in the table, level on points (13) with fifth-placed Everton, and here Sports Mole rounds up the team news for the two sides.
Doubtful: Luke Shaw (illness)
Sports Mole's predicted XI: De Gea; Wan-Bissaka, Lindelof, Varane, Shaw; Matic, Fred; Greenwood, Fernandes, Pogba; Ronaldo
Doubtful: Jordan Pickford (shoulder), Alex Iwobi (knock)
Sports Mole's predicted XI: Pickford; Godfrey, Mina, Keane, Digne; Townsend, Doucoure, Allan, Iwobi; Gray; Rondon