Manchester United travel to Belgium on Thursday evening for the first leg of their Europa League last-32 tie with Club Brugge.
The Red Devils cruised through the group stages and are the second favourites to win the competition behind Italian giants Inter Milan.
Ole Gunnar Solskjaer's men enter the knockout rounds in good domestic form after winning three and drawing one of their last four matches, including a 2-0 win over Chelsea on Monday.
Here, Sports Mole rounds up United's latest injury and suspension news ahead of the clash with Brugge.
Paul Pogba
Status: Out Type of injury: Ankle Possible return date: February 23 (vs. Watford)
Paul Pogba underwent ankle surgery last month and only returned to training this week, meaning this match will come too soon for his return. The France international continues to be strongly linked with a move away from Old Trafford but will be at the club until at least the summer.
Marcus Rashford
Status: Out Type of injury: Back Possible return date: Unknown
Marcus Rashford is not expected to return until at least March having suffered a stress fracture to his back against Wolves on January 15. The England international had been in fine form for the Red Devils, scoring 19 times in all competitions this term from a wide position.
Scott McTominay
Status: Major doubt Type of injury: Knee Possible return date: February 20 (vs. Club Brugge)
Scott McTominay has been on the sidelines since picking up a knee injury against Newcastle United on Boxing Day. The Scotland international was recently ruled out for "a few months" by Solskjaer, but he took part in warm-weather training last week and is closing in on a comeback.
Axel Tuanzebe
Status: Major doubt Type of injury: Hamstring Possible return date: February 20 (vs. Club Brugge)
Axel Tuanzebe has been out with a hamstring problem since the middle of December. The defender is thought to be making good progress in his recovery, however, and could be available for the clash with Brugge this week.
Victor Lindelof
Status: Minor doubt Type of injury: Illness Possible return date: February 20 (vs. Club Brugge)
Victor Lindelof missed out on selection against Chelsea on Monday due to illness, but it is not thought to be serious enough to keep him out for a second game running.
MANCHESTER UNITED'S SUSPENSION LIST
United have no players suspended for Thursday's trip to Belgium.