The pair have been heavily linked with summer moves to a number of elite clubs, including English outfits City and Chelsea.
"Cavani and Falcao would work in England," Mancini told The Guardian. "They have experience. Both players are 26, 27. They are good enough to play in England."
Meanwhile, Mancini has hit back at suggestions that he could be replaced at the Etihad Stadium in the summer.