In defence, Bacary Sagna has shaken off an ankle knock sustained while on international duty for France to start at right-back, while new arrival Nicolas Otamendi has to settle for a place alongside De Bruyne on the bench.
For Palace, there are three changes as Martin Kelly and Brede Hangeland replace injured pair Joel Ward and Damien Delaney in defence, while Yannick Bolasie comes in for the absent Connor Wickham up front.
Crystal Palace: McCarthy; Kelly, Dann, Hangeland, Souare; McArthur, Cabaye; Zaha, Puncheon, Sako; Bolasie
Subs: Hennessey, Mariappa, Jedinak, Lee, Mutch, Gayle, Campbell
Manchester City: Hart; Sagna, Kompany, Mangala, Kolarov; Fernandinho, Toure, Nasri, Navas; Bony, Aguero
Subs: Caballero, Demichelis, Otamendi, Garcia, Roberts, Iheanacho, De Bruyne
See Sports Mole's prediction for the game below.
Follow minute-by-minute commentary of the match on Sports Mole here.