The Saints entered the match in 18th position in the table, and having not won a league game on home soil in 2018.
Read how it all unfolded in Sports Mole's minute-by-minute live commentary of the action below.
SOUTHAMPTON: McCarthy; Cedric, Yoshida, Hoedt, Bednarek, Bertrand; Romeu, Hojbjerg; Ward-Prowse, Tadic; Long
CHELSEA: Courtois; Azpilicueta, Christensen, Cahill; Zappacosta, Kante, Fabregas, Alonso; Willian, Morata, Hazard
4 - Chelsea have won their last four league games against Southampton – they've never won five in a row against them. Roll. pic.twitter.com/oK8zA05sRo— OptaJoe (@OptaJoe) April 14, 2018