Bowyer will be without Ruben Rochina, who was bright in the early stages at Pride Park on Sunday but was stretched off with a dislocated shoulder. He's now expected to miss up to three months of action.
Rochina was replaced by Leon Best on the day and it's likely that Best will start in his place after scoring Blackburn's late equaliser.
Meanwhile, visitors Forest have begun their season with two straight wins at home.
Billy Davies, who made a number of changes for Hartlepool's visit, has no fresh injury concerns and could start with the same XI that beat Huddersfield.
The last meeting between these two sides was at Ewood on New Year's Day, when Blackburn put three unanswered goals past Forest.
Possible starting lineups
Blackburn: Kean; Kane, Hanley, Dann, Spurr; Judge, Lowe, Marrow, King; Best, Rhodes
Forest: Darlow; Lichaj, Hobbs, Collins, Cohen; Mackie, Lansbury, Guedioura, Reid; Derbyshire, Cox
Sports Mole says: 1-1