The Saints are currently five points clear of fifth-placed Gloucester Rugby in the table with two games left to play.
However, they will be wary of a Sale side who hammered Gloucester 32-9 last weekend.
Northampton: Foden, K Pisi, May, Burrell, Elliott, Myler, Dickson, Tonga'uhia, Hartley, Mujati, Lawes, Day, Wood, Dowson, Van Velze
Replacements: Haywood, Waller, Doran Jones, Manoa, Clark, Roberts, Lamb, Wilson
Sale: Haley, Brady, Cueto, Leota, Amesbury, Cipriani, Peel, Harrison, Taylor, Thomas, Myall, Holmes, Vernon, Seymour, Gaskell
Replacements: Jones, Flynn, Croall, Beaumont, Doyle, Fowles, James, Ingall
Sports Mole says: Northampton to seal the win