Sale Sharks head coach Bryan Redpath returns to Gloucester for the first time on Saturday following his resignation seven months ago.
The Aviva Premiership's bottom-placed side can win back-to-back league matches for the first time this season if they triumph in the West Country.
Following two defeats, Gloucester got back on track last weekend thanks to a 46-20 victory over London Welsh in the LV= Cup.
Jim Hamilton and Charlie Sharples return for the hosts, while Dan Murphy and Sione Kalamafoni also come into the starting XV.
Recent form:
Gloucester: WWWLLW
Sale: WLLWLW
Lineups:
Gloucester: Cook, Sharples, Tindall, Twelvetrees, Monahan, Burns, Cowan, Murphy, Edmonds, Harden, James, Hamilton, Savage, Qera, Kalamafoni
Replacements: Britton, Wood, Knight, Buxton, Cox, Robson, Molenaar, Thomas
Sale: Miller, Amesbury, Addison, Tuitupou, Cueto, Cipriani, Peel, Harrison, Taylor, Buckley, McKenzie, Myall, Vernon, Seymour, Powell
Replacements: Ward, Lewis-Roberts, Cobilas, Holmes, Gaskell, Cliff, Macleod, Shepherd
Sports Mole says: Gloucester to emerge triumphant
Jack Prescott
