The Togolese striker missed last weekend's heavy defeat to Liverpool through injury but has recovered in time for tonight's match.
Sunderland, meanwhile, make two changes of their own as Adam Johnson comes back into the starting lineup in place of Connor Wickham, while John O'Shea is dropped to the bench in favour of Carlos Cuellar.
Tottenham: Lloris; Naughton, Chiriches, Kaboul, Rose; Lennon, Chadli, Paulinho, Eriksen; Adebayor, Kane
Subs: Friedel, Fryers, Veljkovic, Bentaleb, Sandro, Sigurdsson, Townsend
Sunderland: Mannone; Bardsley, Alonso, Brown, Cuellar; Vergini, Ki, Bridcutt, Cattermole, Johnson; Borini
Subs: Larsson, Gardner, Wickham, Colback, O'Shea, Scocco, Ustari
You can follow live coverage of the match with Sports Mole by clicking here.