The Citizens – who lost 2-0 against Mauricio Pochettino's side in September – can finish top of Group A and book their place in the last 16 if they secure all three points against Les Parisiens.
The most notable absentees from City's matchday squad are English midfielders Phil Foden and Jack Grealish, while Kevin De Bruyne is unavailable once again after testing positive for COVID-19 last week.
Your City XI to face PSG! 💪— Manchester City (@ManCity) November 24, 2021
XI | Ederson, Walker, Dias, Stones, Cancelo, Rodrigo, Gundogan (C), Zinchenko, Mahrez, Bernardo, Sterling
SUBS | Steffen, Carson, Ake, Jesus, Laporte, Fernandinho, Palmer, McAtee#ManCity pic.twitter.com/Hg7235LqbM
After being rested in the 3-0 victory against Everton on Sunday, Ruben Dias has returned to the first XI, joining Kyle Walker, John Stones and Joao Cancelo in the back four, with Aymeric Laporte dropping to the bench.
Academy graduates Cole Palmer and James McAtee, who both featured at the weekend, have been selected on the substitutes' bench, along with Gabriel Jesus who misses out of the first XI for the second successive match.