Mauricio Pochettino's side will travel to Stamford Bridge on Easter Sunday in the hope of winning their fifth top-flight game in a row.
"It's true, it's a big game and I can't wait for it," Moura told the club's official website. "I'm excited to be around, to hopefully be involved and I believe firmly that we can win.
"This year we are very good - we've had great games against Manchester United, Arsenal and even against Juventus over the two matches, so I'm sure we can produce a great game against Chelsea also because I think we are very, very talented.
"I've been waiting for this kind of match. The Premier League is the best league in the world and I'm happy to be here and to hopefully be involved in a London derby like this. It's a big, big match, I'm excited for it and this week we will all prepare very well for it."
Moura has made six appearances for the North London outfit since his move from Paris Saint-Germain in January, and only two of those outings have been in the league, both of which were as a substitute.
Tottenham currently sit fourth in the table.