Chelsea boss Frank Lampard expects to have defender Andreas Christensen available for the Premier League game with Brighton at Stamford Bridge.
Centre-back Christensen has returned to training after suffering a knee knock in last weekend's loss to Liverpool, but left-back Emerson Palmieri, who sustained a thigh problem in that game, will miss out.
Brighton will be without centre-back Shane Duffy after the Republic of Ireland international suffered a calf problem in the midweek Carabao Cup defeat against Aston Villa.
Glenn Murray (ankle) should be available having returned to training, while Iran forward Alireza Jahanbakhsh could come into contention again following an injury picked up during the international break.
Chelsea provisional squad: Arrizabalaga, Azpilicueta, Tomori, Christensen, Alonso, Kante, Jorginho, Kovacic, Mount, Willian, Abraham, Caballero, James, Zouma, Barkley, Pedro, Hudson-Odoi, Pulisic, Batshuayi, Giroud.
Brighton provisional squad: Ryan, Dunk, Webster, Montoya, Burn, Stephens, Gross, Mooy, Propper, Maupay, Alzate, Button, Bong, Baluta, Bissouma, Murray, Connolly, Jahanbakhsh.