The Titans were looking for a quarterback in the 2011 Draft and were linked with Kaepernick, but instead chose to draft Jake Locker in the first round.
"It's something I definitely haven't forgotten," Kaepernick told The AP.
"I thought I was someone they were interested in. Whether it was then or later, I didn't know, but it's in the past now."
The 49ers face the Titans on Sunday at LP Field.