The 49ers crushed the Jacksonville Jaguars 42-10 in the second game of the International Series to secure their fifth successive win.
Harbaugh told reporters: "The preparation was outstanding. The players dialed in, did a great job in practice and off the practice field, in their free time. We were real good, curfews were 100% each night."
The 49ers are 6-2 in their season after week eight.