Joe Philbin's team travel to the Mercedes-Benz Superdome to face the Saints in a clash between two of the unbeaten teams in the NFL going into week four.
"I've known him since we were so small, about 5 or 6 years old," Wallace told the Times-Picayune. "I haven't played against Keenan since we were young like that.
"I've always been on his team, so this is a little different. I'm excited. I'm up for the challenge. I know he's up for the challenge, so it's going to be a good time."
Wallace has 12 receptions for 152 yards this season as well as one touchdown.