Guidolin, who recently took over in South Wales, knows 26-year-old Paloschi from his time in Serie A and the two worked together at Parma.
It was reported last night that an £8m fee had been agreed with Chievo for the former Italy Under-21 international, and Guidolin was asked about the potential move in his first pre-match news conference as Swans boss this afternoon.
He told reporters: "Paloschi was my player when we worked together at Parma. He was a promising player. He is a good player, a good guy. I think he is important for us and can help the team to have results and score many goals, I hope.
"I think he's a modern player. He can play well in the Premier League because he is strong."
A new striker seems to be Swansea's top priority in the final four days of the transfer window, with Crystal Palace's Dwight Gayle reportedly also targeted by the Premier League strugglers.