The 20-year-old, who joined the Red Devils from Blackburn Rovers in a £16m summer 2011 switch, has mainly been used at right-back or in midfield by manager Sir Alex Ferguson.
Reports have linked the Old Trafford outfit with a move for a new centre-half in January, but Jones is confident he can be the mainstay of United's defence in the future.
"I've always said that my favourite position and the one I feel most comfortable in is centre-half," he told the club's official website.
"But if playing in different positions helps me become a better player then that's great.
"If I am asked to play in a certain situation then I will play there because I enjoy playing football."
Injuries have limited Jones to just seven United appearances this season.