Rooney has attracted criticism in the early stages of the season following a handful of lacklustre performances on the pitch.
The 30-year-old has played in a deeper role on occasion, but last night started up front as he registered just one shot on target in a 3-1 victory over Northampton Town in the third round of the EFL Cup.
Despite Rooney's recent performances, Ince has given his backing to the player, claiming that the England international is an easy target.
"Everyone can jump the gun and say 'drop Rooney' because he's a standout high-profile player who isn't performing, but if you drop him who do you play instead?" Ince wrote in his Paddy Power blog.
"There's no-one at Manchester United who is better than him as a number 10. Rooney shouldn't be in midfield. End of.
"You're talking about England's greatest goalscorer, and you're wasting him in midfield. When he plays that position he comes too deep to get on the ball, and you really need him in the final third."
United will try to avoid three successive Premier League defeats when they take on the defending champions Leicester City at the weekend.