Inter stumbled to a 3-0 defeat at the hands of Tottenham Hotspur at White Hart Lane in the first leg of the round-of-16 tie in midweek, but they will need to regain focus as they try to push for a top-three spot in the league table.
Bologna, who are safe in the middle of the standings, can record their third victory in a row if they are able to upset Inter at the San Siro this weekend.
Inter Milan: LWDWL
Possible starting lineups
Inter Milan: Handanovic; Zanetti, Chivu, Pereira, Juan; Schelotto, Alvarez, Guarin, Kuzmanovic, Gargano; Palacio
Bologna: Curci; Morleo, Cherubin, Sorensen, Garics; Taider, Perez, Kone; Gilardino, Gabbiadini, Diamanti
Sports Mole says: 2-1