The Tennessee Titans have highlighted Jamaal Charles as the main threat for the Kansas City Chiefs this weekend.
The running back has 289 rushing yards, 213 receiving yards and four touchdowns from the first four games of the season.
Safety George Wilson told Titans' official website: "You see a guy like Charles, there's not many guys who have more touches than he does at this point in the season.
"He leads their team in rushing and receiving, so we know their offense goes through Charles first and foremost but they have [Dexter] McCluster and [Dwayne] Bowe, guys they can get the ball to that can make big plays as well."
Defensive tackle Jurrell Casey added: "A lot of times they like to stretch the ball out and use his speed so it's going to be one of those games where we've got to expect our defensive ends to set the edge and let everybody else get to him in time because once he hits that corner, it's kind of hard to get up to him, to keep up with him."
The Chiefs, who play at Tennessee tomorrow, are yet to lose a game in 2013.
