Last season's NFC West champions beat their divisional rivals 35-11, securing their first victory since the opening week of the season.
The running back told reporters: "The 49ers are all about winning. It was a get-back-on-track game. We knew we couldn't lose again.
"[Left guard Mike] Iupati did a great job. I just read it. I have to give [Colin Kaepernick] some love, everyone was dogging him. As long as we're the 49ers we'll be alright."
Gore recorded 153 rushing yards and a touchdown last night.