Smith said that he has spent a lot of time in the Bay area and cannot wait to take them on at the Chiefs' home ground.
"I'm excited for this," he told CSN Sports. "I've played a lot of football in the Bay Area, pretty close to Oakland.
"I'm familiar with them after being in the area so long. I'm excited about it. I'm pumped."
Smith joined the Chiefs this season from the San Francisco 49ers.