The NFC North side have taken six sacks and forced 11 fumbles in their first four games of the season.
The Saints quarterback told reporters: "Obviously history has not treated us well in Soldier Field, so obviously we all want to be able to go up there, play well and get a win. I know the Bears are coming off of a tough loss in the division, so they are going to be ripe and ready to play us.
"We need our best, there's no doubt about it. I think this week, a lot of it's about recovery from the game, preparation, just being really really sharp, getting your bodies ready to go, and then getting your mind right to go up there and battle it out and get a tough win.
"It's going to be a physical game. They're a physical team, they do a lot of things very, very well defensively. You see it in the way they play, what they preach. It's all about flying to the ball, hitting you hard, trying to get the ball out. They do it better than anybody in the league, so it's something we've got to be prepared for."
The Saints are unbeaten so far this season.