Calvin Johnson and Reggie Bush leave field for Detroit Lions during week five

The Detroit Lions have potentially suffered two injury blows with both Calvin Johnson and Reggie Bush having to leave the field during their week five fixture.

The two players left the green on Sunday as the Lions took on the Buffalo Bills, with Bush potentially picking up a troublesome ankle injury, while Johnson limped off the park after his first catch.

No news has been revealed on either player's status, with more information expected to come out later on Sunday evening or Monday morning.

The Lions lost out to the Bills by three points, as Jim Caldwell's side came up short in a 17-14 defeat at home at the Ford Field.