The Owls are 20th and unbeaten in three games as they battle for survival in the Championship.
Meanwhile, Gus Poyet's men are among a clutch of teams battling for the four playoff spots.
At the moment, the Seagulls are unbeaten in their last four games and are just five points off sixth-placed Middlesbrough.
Sheff Wed: WDLWDW
Sheff Wed: Kirkland, Buxton, Llera, Gardner, R Johnson, Prutton, Johnson, Pugh, Coke, Antonio, Lita
Brighton: Kuszczak; Greer, El-Abd, Calderon, Bridge; Hammond, Orlandi, Buckley, Bridcutt; Barnes Mackail-Smith
Sports Mole says: 1-1