The striker, who recently returned from serious injury, was left out of Saturday's win at Stoke City.
Elsewhere, James McClean comes into midfield in place of David Meyler.
Boro have made two changes to the team that drew with Crystal Palace as Julio Arca comes in for Faris Haroun, while Curtis Main is chosen in attack ahead of Marin Emnes.
Middlesbrough: Steele; Hoyte, Bennett, Bates, Hines; McMahon, Arca, R Williams, Thomson; Main, Jutkiewicz
Subs: McManus, Emnes, Ogbeche, Martin, Smallwood, Reach, Ripley
Sunderland: Mignolet; Bardsley, Richardson, Turner, O'Shea; Larsson, McClean, Colback, Gardner; Sessegnon, Campbell
Subs: Elmohamady, Dong-won, Wickham, Lynch, Reed, Meyler, Westwood