The home side led 1-0 at the interval courtesy of a cool penalty from skipper Yaya Toure.
Toure converted his second from the penalty spot early in the second period after Fernando Amorebieta had brought down David Silva inside the box - with the centre-back dismissed from play for the rash challenge.
Read how it all unfolded in Sports Mole's minute-by-minute live commentary of the action below.
CITY: Hart; Zabaleta, Lescott, Demichelis, Kolarov; Fernandinho, Toure; Milner, Nasri, Silva; Negredo
FULHAM: Stockdale; Heitinga, Hangeland, Amorebieta, Riise; Kacaniklic, Riether, Kvist, Sidwell, Richardson; Woodrow
126 - If #MCFC score today, they will set a new record for their most goals scored in a single season (126). Formidable.— StatCity (@StatCity) March 22, 2014
7 - Yaya Toure's hat-trick is the 7th so far in the Premier League this season, but Man City's first in the PL since April 2012. Treble.— OptaJoe (@OptaJoe) March 22, 2014