Antonio Conte, meanwhile, has made eight changes from the team that beat Sweden, with goalkeeper Salvatore Sirigu in for the rested Gianluigi Buffon and Simone Zaza and Ciro Immobile leading the line.
Ireland are still in with a chance of making the last 16 of the tournament if they beat the Azzurri, who are assured of top spot in the group whatever happens.
Italy: Sirigu; Barzagli, Bonucci, Ogbonna; Bernardeschi, Sturaro, Motta, Florenzi, De Sciglio; Zaza, Immobile
Republic of Ireland: Randolph; Coleman, Duffy, Keogh, Ward; Hendrick, McClean, McCarthy, Brady; Murphy; Long
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