In total, Malta and Italy have met on six separate occasions, with Italy winning all of those matches. Malta also enter the game having not won a single match since last November, when they beat the Faroe Islands 3-2 in a friendly on their own patch.
In Group H, Malta opened with a 2-0 defeat in Croatia, before suffering a 3-0 loss at home to Norway on Friday evening. They are currently ranked 155th in the FIFA rankings, while they have never made it to any major international tournament.
Malta have leading scorer Michael Mifsud fit and available despite a slight concern over the striker's fitness and the 33-year-old, who has scored 39 times in 107 caps, is expected to start in attack alongside Andre Schembri, who has 58 caps to his name.
Italy boss Conte has no fresh injury concerns from Friday's match, but the former Juventus manager could make changes for this fixture, with Marco Verratti and Graziano Pelle both hoping to come into the XI.
Possible starting lineups
Malta: Hogg; Agius, Camilleri, Failla, P Fenech; Briffa, R Fenech, Z Muscat; Mifsud, Schembri, R Muscat
Italy: Buffon; Bonucci, Chiellini, Ranocchia; De Sciglio, Marchisio, Pirlo, Verratti, Darmian; Immobile, Pele
Sports Mole says: 0-3