Visiting Juve began brightly and were presented with a good chance to take the lead in the eighth minute when Cesena defender Vangelis Moras committed a handball inside his own area.
Andrea Pirlo stepped up to take the resultant penalty, but his effort struck the post before being cleared to safety.
Juve continued to dominate for the remainder of the half, but Mirko Vucinic in particular was wasteful in front of goal.
Alessandro Matri shot over the target just after the restart as the Old Lady continued to search for the opening goal of the match.
It finally arrived in the 81st minute when substitute Borriello fired in a headed pass from Vucinic.
Emanuele Giaccherini and Vucinic both missed chances to secure the victory for Juve. However, their misses went unpunished as the Black and Whites moved a step closer to securing the Serie A title.