Andrew Taylor, Michael Hector, Alex Fernandez, Ola John and Orlando Sa all earn starting places, while Danny Williams, Gareth McCleary and Jordan Obita drop to the bench after starting Tuesday's 2-2 draw at home to Huddersfield Town.
Meanwhile, the hosts have made two alterations as they seek to put Tuesday's 1-0 defeat to Leeds United behind them.
Cardiff City: Marshall; Peltier, Morrison, Connolly, Malone; Ralls, Gunnarsson, Pilkington, Noone; Jones, Mason
Subs: Moore, Tamas, Dikgacoi, O'Keefe, Kennedy, Ameobi, Saadi
Reading: Al-Habsi; Gunter, Hector, Ferdinand, Taylor; Norwood, Fernandez; John, Vydra, Blackman; Sa
Subs: Bond, Obita, Hurtado, Williams, McCleary, Cooper, Liburd
Keep abreast of proceedings from the Cardiff City Stadium in Sports Mole's live text commentary.