Winger Silva, 22, joined Bolton on a season-long loan from Arsenal after four years on loan at clubs in Spain meant that he was eligible for a Spanish passport, allowing him to play in the United Kingdom.
Meanwhile, Dutch midfielder Kyle Ebecilio makes his debut for Forest following his loan move from FC Twente.
Bolton have not won in their last eight league games and have failed to score in their last five. They have also failed to beat Forest in their last six attempts, although Nottingham have only won once in their last 11 league appearances.
Bolton Wanderers: Amos; Wilson, Prince, Dervite, Moxey; Davies, Danns, Walker, Silva; Clough, Madine.
Nottingham Forest: De Vries; Lichaj, Mills, Hobbs, Pinillos, Mancienne; Antonio, Ebecilio, Osborn, Lansbury; Walker.